BioTwin
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BioTwin/Science & research

The science of a more personal future

Understand the person.
Reimagine the possibilities.

Our ambition is a human virtual twin for every person: a biological reference that evolves over time and helps bring personalized, precise and proactive medicine within reach.

The BioTwin method

From your biology
to your virtual twin.

How the twin takes shape

BioTwin brings advanced measurement and proprietary modeling together. The result is a connected representation of your biology, designed to gain context with every new observation.

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  1. A conceptual close-up of biological signals within a small blood sample

    Collect biological information

    Collection and personal context

    At-home sampling and personal context provide the starting point. Repeat collections create a history of your biology.

  2. Read the signals

    Metabolomics, explained

    Analytical chemistry, including high-resolution mass spectrometry and metabolomics, examines the small molecules that reflect biological activity.

  3. Build Bio-Signatures

    Explore this Bio-Signature

    Advanced analytics connect related signals into proprietary Bio-Signatures, making complex biological patterns easier to explore.

  4. Reconstruct and update

    Your reference over time

    BioTwin's virtual model brings those patterns together with your context. New observations update your personal reference and reveal the story across time.

Five windows on biology: DNA, epigenetics, RNA, proteins and metabolites.

Science, in human terms

Metabolites
tell your biological story.

Metabolomics explores part of biological activity, complementing the other omics.

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In French

The wider research landscape

New questions.
More possibilities.

Beyond the first medical roadmap, BioTwin's research explores connections across oncology, neurology, cardiovascular function, women's health, fatigue and metabolism.

01

Oncology

A more personal approach to early detection.

Research focus

Breast · Colorectal · Lung · Pancreatic · Prostate · Ovarian

Cancer Bio-Signatures lead the medical roadmap, with breast and colorectal applications at the forefront of the UAE clinical pathway.

Explore oncology
02

Neurology

New insight into complex neurological conditions.

Research focus

Parkinson's · Dementia · Depression · Epilepsy

Research explores whether metabolic patterns can add useful biological context to conditions that are often difficult to characterize.

Explore neurology
03

Cardiology

Understand the biology behind cardiovascular change.

Research focus

Heart failure · Hypertension

Cardiovascular research extends the platform toward a more personal view of risk, physiological change and clinical follow-up.

Explore cardiology
04

Metabolic health & beyond

Connect the systems that shape everyday health.

Research focus

Pre-diabetes & obesity · Women's health · Allergy, immunity & sensitivity · ME/CFS

These programs explore the links between metabolism, symptoms, lifestyle and longer-term health.

Explore the research

These are research and development areas. Medical access is currently through participating physicians in the United Arab Emirates.

The horizon

Medicine that knows
your story.

The long-term vision

Our vision reaches from recognizing meaningful biological change to supporting more personal care, exploring individual responses and, ultimately, testing possibilities in a virtual representation of you.

Today, the same technological foundation also powers TwinMe programs for people who want to explore their biology and take an active role in their health.

Explore TwinMe programs
Conceptual view of a clinician exploring a patient's biological context

The evidence, in depth

Open the research.
Follow the progress.

Publications and announcements, with the question studied and the stage of validation.

The virtual twin foundationDigital Twin · 29 May 2024 · Journal article

BioTwin's foundational paper describes the Human Virtual Twin framework and individual biological profiling. It establishes the technology's scientific foundation and the idea of a personal biological reference.

Read the journal article
Individual identification through metabolic profilesDigital Twin · 21 August 2026 · Journal article

A peer-reviewed study of 1,257 participants, 18,288 samples and 134 analytical batches identifies individuals from their metabolic profiles with 94% user-level accuracy. It addresses biological individuality and repeat measurement.

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Metabolic signatures associated with breast cancermedRxiv · 27 April 2026 · Preprint

A retrospective case-control study includes 2,734 participants: 114 diagnosed breast cancer cases and 2,620 controls. It investigates breast cancer-associated metabolic signatures and identifies prospective evaluation in asymptomatic populations as a next step.

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Post-exertional malaise-like fatiguemedRxiv · 10 June 2026 · Preprint

An exploratory cohort study examines metabolic patterns associated with self-reported post-exertional malaise-like fatigue in 1,784 participants, adding to BioTwin's research beyond oncology.

Read the preprint
Clinical collaboration in Abu DhabiAbu Dhabi Media Office · 31 January 2025 · Institutional announcement

The institutional announcement describes Cleveland Clinic Abu Dhabi's collaboration with BioTwin on a breast cancer pilot. It records Department of Health approval for research purposes at that date. The current medical access pathway is described separately on BioTwin's oncology pages.

Read the institutional announcement

Preprints present research before peer review. Dates above refer to the publicly posted version.

BioTwin’s public ecosystem

A larger world
behind the twin.

Medical research, public support and technology expertise all play a part in bringing human virtual twins into the world.

Healthcare & research

Government & investment

Technology & advisors

Organizations presented in BioTwin's public ecosystem. Specific roles and sources are detailed below.

Roles and institutional sources

Organizations and programs presented in BioTwin's public ecosystem. The documented breast cancer pilot with Cleveland Clinic Abu Dhabi and its research authorization are described in the institutional announcement.

Cleveland Clinic Abu Dhabi

Breast cancer research pilot

A clinical collaboration announced on 31 January 2025.

Department of Health, Abu Dhabi

Research authorization

The 2025 announcement records approval for the pilot for research purposes.

Read the institutional announcementExplore the public ecosystem

In the news

The story,
in other voices.

Explore television reports, interviews and journalism about BioTwin, its technology and its medical ambition. Coverage is primarily in French.

More media coverage